The San Francisco 49ers suffered their first loss of the 2025 campaign on Sunday and that has allowed the Los Angeles Rams and Seattle Seahawks to catch them for the best record in the NFC West.

What’s at stake, injuries, a key matchup to watch, TV info, a fantasy sleeper and a final score prediction for Thursday night’s game between the NFC West rivals.

San Francisco's Eddy Pineiro booted a 41-yard field goal in overtime and the 49ers defense came up big in a tense 26-23 NFL victory over the Los Angeles Rams on

Viewers raised their eyes late in the game when Amazon Prime broadcast play-by-play man Al Michaels said that the banana Jones was eating on the sideline in that moment was his 11th of the game. Afterward, Jones clarified it hadn't been quite that many.

The San Francisco 49ers suffered a major blow with Nick Bosa’s ACL injury, and one of his teammates revealed how much the team was affected during this NFL season.

Get bBetting insights for TNF 49ers vs Rams, including BetMGM odds, betting splits, injury reports, and key stats for this NFC West primetime showdown.