San Francisco 49ers' ever-improving defensive tackle Alfred Collins came off the bench to provide one of the biggest plays Thursday night. "His progression is kind of scary." ...

The 49ers pulled off one of the shocking upsets of the early NFL season, ignoring multiple injuries for a 26-23 overtime victory over the Rams.

The 49ers defeated the Rams 26-23 in overtime behind a terrific performance from Mac Jones, another workmanlike effort from Christian McCaffrey, a career night from Kendrick Bourne and several clutch ...

The Los Angeles Rams and San Francisco 49ers had a light week of practice due to the quick turnaround from Sunday’s games to Thursday night’s matchup, attempting to keep players fresh without wearing ...

The Los Angeles Rams didn’t practice on Monday after just playing a game the day before, taking a lighter approach to the week with a game on Thursday night against the San Francisco 49ers. They did ...

A full-on quarterback controversy might not be brewing for the San Francisco 49ers, but after picking up his third win of the season, backup Mac Jones has certainly taken control of the conversation.

The San Francisco 49ers' defensive line faced another blow as Yetur Gross-Matos suffered a hamstring injury during their October 2, 2025, Thursday Night Football game, ruling him out. This adds to a ...

The San Francisco 49ers released their latest injury updates headed into the Week 5 contest versus the Los Angeles Rams.

Former 49ers safety Donte Whitner explains what San Francisco is missing on offensive without receiver Deebo Samuel.

USA Today's NFL experts make their picks for a Week 5 showdown between the Los Angeles Rams and San Francisco 49ers ...

Missing a plethora of key starters, back-up quarterback Mac Jones led the depleted San Francsico 49ers to a thrilling 26-23 overtime victory over the Los Angeles Rams on Thursday Night Football.

Who won the Arizona Cardinals vs San Francisco 49ers game? Check out our updates, highlights and analysis from the NFL Week 3 game.