The 49ers pulled off one of the shocking upsets of the early NFL season, ignoring multiple injuries for a 26-23 overtime ...

The Rams failed to score on their final possession when Kyren Williams got stuffed on fourth-and-1 to seal the 49ers' win.

San Francisco's defense was playing well Sunday, and came up with a big-time play to open the fourth quarter. Defensive end ...

The San Francisco 49ers will take on the Seattle Seahawks in Week 1 of the NFL season on Sunday at Lumen Field.

On Sunday afternoon the San Francisco 49ers were faced with even more injury adversity when star tight end George Kittle left the game with a hamstring injury in the first half of a 17-13 win over the ...

Kyle Shanahan's team could be without quarterback Brock Purdy for nearly a month after the San Francisco 49ers won their opening NFL game. San Francisco 49ers quarterback Brock Purdy celebrates after ...

The San Francisco 49ers suffered a major loss on the offensive side of the ball during Sunday’s win. All-Pro tight end George Kittle suffered a hamstring injury during the first half of Sunday’s 17-13 ...

Go on the field with 49ers players during the team's 16-15 victory over the Arizona Cardinals. Listen in as San Francisco 49ers LB Fred Warner was wired for sound during the team's Week 4 matchup ...

Sept. 9 (UPI) --The San Francisco 49ers will place tight end George Kittle on injured reserve due to his hamstring injury, prompting a mandatory absence of at least four games. Sources told NFL ...

NFL kicker Jake Moody faced the consequences even as the San Francisco 49ers were able to pull out a victory against the Seattle Seahawks in Week 1. The 49ers waived Moody on Tuesday after a brutal ...

The San Francisco 49ers beat the Seattle Seahawks on Sunday, but it was not an easy victory. There are certainly some things that the 49ers will want to clean up, and some questions that could hold ...

After a long offseason, the San Francisco 49ers traveled to Washington for a Week 1 battle with the Seattle Seahawks at Lumen Field and walked out with a 17-14 win and in a three-way tie for the top ...