Background Hereditary transthyretin amyloidosis (ATTRv) is a rare multisystem disorder with marked phenotypic heterogeneity.
Background The relationship between pericardial inflammation and subsequent constriction in tuberculous (TB) pericarditis remains poorly understood. Late gadolinium enhancement (LGE) has shown ...
The natural history of symptomatic severe aortic stenosis (AS) heralds a poor prognosis—a paradigm that rightly drives valve ...
Background Atrial fibrillation (AF) is a common cause of ischaemic stroke and a major global health burden, but is often ...
Background Out-of-hospital cardiac arrest (OHCA) in children is a rare but devastating event, with an estimated incidence of ...
Background Heart failure (HF) remains associated with high mortality worldwide despite advances in guideline-directed therapy ...
Objective To evaluate trends, early clinical outcomes and surgeon-variation and hospital-variation in trainees performing isolated aortic valve replacement (AVR) and mitral valve (MV) surgery, ...
Background Activities of daily living (ADL) are frequently impaired in patients with atrial fibrillation (AF). Although the 6-Minute Walk Test (6MWT) is widely used for functional assessment, it ...
Background Atrial fibrillation (AF), elevated heart rate and elevated high-sensitivity cardiac troponin T (hs-cTnT) are common in sepsis, but their independent and combined prognostic significance ...
Background Guidelines permit up to 360 J for synchronised biphasic electrical cardioversion (ECV) in atrial fibrillation (AF) lasting >48 hours. The CHESS randomised trial reported higher first-shock ...
Background Persistent atrial fibrillation (AF) remains challenging to treat with catheter ablation. The left atrial posterior wall (PW) may represent an important non-pulmonary vein (PV) substrate; ...
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