The San Francisco 49ers look to keep their unbeaten streak alive against the team that dominated them twice to end last season. Here's how ...

Christian McCaffrey and wife Olivia Culpo welcome their second child, Roman Augustus, as San Francisco prepares for its Week ...

Linebacker Dre Greenlaw played with added emotion in Week 4 against his former team.And the NFL determined he took it a ...

The 49ers have released veteran defensive lineman Matthew Judon from their practice squad ahead of Sunday's Week 5 matchup ...

Defensive lineman Mykel Williams is officially on the 49ers’ 53-man roster and is expected to play Sunday against the Seattle ...

The 49ers activate Mykel Williams and announce two other roster moves ahead of Sunday's crucial matchup against the Seahawks ...

The San Francisco 49ers made a couple of roster moves to bolster their depth on both sides of the ball before facing the ...

Kyle Shanahan reveals how Dre Greenlaw's aggressive play and intensity have energized the defense and inspired teammates to ...

The 49ers need Brock Purdy to stay patient against the Seahawks. Kyle Shanahan explains why forcing plays could lead to sacks ...

The 49ers take their 4-0 record to Seattle. Brock Purdy, Christian McCaffrey and three key defenders must deliver to keep San ...

Kyle Shanahan explains why Mike Evans is a matchup nightmare for defenses and praises the receiver's toughness after playing through a rib inju ...