Many learners are more facile with the use of large language models in medicine than their supervisors are. The authors ...

The FDA has begun soliciting feedback to inform the next version of the Prescription Drug User Fee Act. User fees remain ...

Plague is a high-consequence infectious disease with epidemic potential. Current treatment guidelines are based on weak evidence. We enrolled persons (excluding pregnant persons) in Madagascar who ...

The authors review available data on the benefits and risks of testosterone treatment in middle-aged and older men with moderate hypogonadism.

Plague is a curious disease. It occurs on multiple continents but only rarely; it is curable with antibiotics but deadly when treatment is delayed. Plague killed millions during three major pandemi ...

Although xenon may have neuroprotective effects, there is no strong evidence that it aids in short-term, high-altitude performance. Success is more likely a result of acclimatization, oxygen suppor ...

A 28-year-old woman was admitted to the hospital because of severe hypoxemia and right heart failure that had been caused by rapidly progressive pulmonary hypertension. A diagnosis was made.

Cutaneous squamous-cell carcinoma (SCC) is primarily caused by oncogenesis mediated by ultraviolet radiation, and β-human papillomavirus (β-HPV) is believed to be a mere facilitator that is ...

For patients with both chronic kidney disease and type 2 diabetes, whether combination therapy with finerenone and empagliflozin would improve outcomes over single-drug therapy is unclear. New ...

The rate of fatalities on U.S. roadways is much higher than those in many other high-income nations. The authors review evidence-based strategies for moving toward a future with no traffic deaths.

A man from rural India presented with redness and blurry vision in one eye. Examination was notable for panuveitis and a live worm in the posterior segment; the worm was removed in a pars plana vit ...

ESR1 mutations can emerge during first-line therapy and lead to endocrine resistance in advanced breast cancer. New research findings on switching to camizestrant after the detection of an ESR1 ...